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  1. Growth-temperature stress causes biochemical changes in the cells and reduction of biomass yield. Quantitative proteome of Arthrospira platensis C1 in response to low- and high temperature stresses was previously...

    Authors: Pavinee Kurdrid, Phutnichar Phuengcharoen, Jittisak Senachak, Sirilak Saree and Apiradee Hongsthong
    Citation: BMC Molecular and Cell Biology 2020 21:43
    Content type: Research article Published on:

  2. Stress is an important cause of skin disease, including hair loss. The hormonal response to stress is due to the HPA axis, which comprises hormones such as corticotropin releasing factor (CRF), adrenocorticotr...

    Authors: Eun Young Lee, You Jin Nam, Sangjin Kang, Eun Ju Choi, Inbo Han, Jinwan Kim, Dong Hyun Kim, Ji Hae An, Sunghou Lee, Min Ho Lee and Ji Hyung Chung
    Citation: BMC Molecular and Cell Biology 2020 21:42
    Content type: Research article Published on:

  3. Localization of neurokinin 1 receptor (NK1R), the endogenous receptor for neuropeptide substance P (SP), has already been described for the right atrium (RA) of the heart. However, the biological role of SP/NK1R ...

    Authors: Yun-Mi Jeong, Xian Wu Cheng, Kyung Hye Lee, Sora Lee, Haneul Cho and Weon Kim
    Citation: BMC Molecular and Cell Biology 2020 21:41
    Content type: Research article Published on:

  4. In the poultry and livestock industries, precise genetic information is crucial for improving economic traits. Thus, functional genomic studies help to generate faster, healthier, and more efficient animal pro...

    Authors: Jeong Hyo Lee, Seo Woo Kim, Ji Seon Han, Seung Pyo Shin, Sang In Lee and Tae Sub Park
    Citation: BMC Molecular and Cell Biology 2020 21:40
    Content type: Research article Published on:

  5. Members of the T-box family of DNA-binding proteins play a prominent role in the differentiation of the three primary germ layers. VegT, Brachyury, and Eomesodermin function as transcriptional activators and, ...

    Authors: Shoshana Reich, Peter Kayastha, Sushma Teegala and Daniel C. Weinstein
    Citation: BMC Molecular and Cell Biology 2020 21:39
    Content type: Research article Published on:

  6. Detailed structural knowledge of enzyme-inhibitor complexes trapped in intermediate state is the key for a fundamental understanding of reaction mechanisms taking place in enzymes and is indispensable as a str...

    Authors: Peter Agback, Esmeralda Woestenenk and Tatiana Agback
    Citation: BMC Molecular and Cell Biology 2020 21:38
    Content type: Research article Published on:

  7. To establish a metabolite fingerprint of ossification of the thoracic ligamentum flavum (OTLF) patients using liquid chromatography-mass spectrometry (LC-MS) in combination with transcriptomic data and explore...

    Authors: Jiahao Li, Lingjia Yu, Shigong Guo and Yu Zhao
    Citation: BMC Molecular and Cell Biology 2020 21:37
    Content type: Research article Published on:

  8. The SMC5/6 complex, cohesin and condensin are the three mammalian members of the structural maintenance of chromosomes (SMC) family, large ring-like protein complexes that are essential for genome maintenance....

    Authors: András Horváth, Gergely Rona, Michele Pagano and Philip W. Jordan
    Citation: BMC Molecular and Cell Biology 2020 21:36
    Content type: Research article Published on:

  9. Fluorescence microscopy is a powerful tool in cell biology, especially for the study of dynamic processes. Intensive irradiation of bacteria with UV, blue and violet light has been shown to be able to kill cel...

    Authors: Nina El Najjar, Muriel C. F. van Teeseling, Benjamin Mayer, Silke Hermann, Martin Thanbichler and Peter L. Graumann
    Citation: BMC Molecular and Cell Biology 2020 21:35
    Content type: Research article Published on:

  10. Deficiency in thymidine kinase 2 (TK2) or p53 inducible ribonucleotide reductase small subunit (p53R2) is associated with tissue specific mitochondrial DNA (mtDNA) depletion. To understand the mechanisms of th...

    Authors: Liya Wang, Ren Sun and Staffan Eriksson
    Citation: BMC Molecular and Cell Biology 2020 21:33
    Content type: Research article Published on:

  11. Neutral cholesterol ester hydrolase 1 (NCEH1) catalyzes the hydrolysis of cholesterol ester (CE) in macrophages. Genetic ablation of NCEH1 promotes CE-laden macrophages and the development of atherosclerosis i...

    Authors: Hiroshi Matsuoka, Riki Tokunaga, Miyu Katayama, Yuichiro Hosoda, Kaoruko Miya, Kento Sumi, Ami Ohishi, Jun Kamishikiryo, Akiho Shima and Akihiro Michihara
    Citation: BMC Molecular and Cell Biology 2020 21:32
    Content type: Research article Published on:

  12. Cytoprotection afforded by mitochondrial ATP-sensitive K+-channel (mKATP-channel) opener diazoxide (DZ) largely depends on the activation of potassium cycle with eventual modulation of mitochondrial functions and...

    Authors: Olga Akopova, Liudmila Kolchinskaya, Valentina Nosar, Iryna Mankovska and Vadim Sagach
    Citation: BMC Molecular and Cell Biology 2020 21:31
    Content type: Research article Published on:

  13. Transmembrane and immunoglobulin domain-containing protein 1 (TMIGD1) is a recently identified cell adhesion molecule which is predominantly expressed by epithelial cells of the intestine and the kidney. Its e...

    Authors: Christian Hartmann, Ysabel Alessa Schwietzer, Daniel Kummer, Nils Kirschnick, Esther Hoppe, Eva-Maria Thüring, Mark Glaesner-Ebnet, Frauke Brinkmann, Volker Gerke, Stefan Reuter, Masanori Nakayama and Klaus Ebnet
    Citation: BMC Molecular and Cell Biology 2020 21:30
    Content type: Research article Published on:

  14. Low concentrations of tumor necrosis factor-alpha (TNF-α) and its receptor TNFR2 are both reported to promote osteogenic differentiation of osteoblast precursor cells. Moreover, low concentrations of TNF-α up-...

    Authors: Yu Zhang, Chengzhe Yang, Shaohua Ge, Limei Wang, Jin Zhang and Pishan Yang
    Citation: BMC Molecular and Cell Biology 2020 21:29
    Content type: Research article Published on:

  16. Progesterone receptor membrane component 1 (PGRMC1) is often elevated in cancers, and exists in alternative states of phosphorylation. A motif centered on PGRMC1 Y180 was evolutionarily acquired concurrently w...

    Authors: Bashar M. Thejer, Partho P. Adhikary, Sarah L. Teakel, Johnny Fang, Paul A. Weston, Saliya Gurusinghe, Ayad G. Anwer, Martin Gosnell, Jalal A. Jazayeri, Marina Ludescher, Lesley-Ann Gray, Michael Pawlak, Robyn H. Wallace, Sameer D. Pant, Marie Wong, Tamas Fischer…
    Citation: BMC Molecular and Cell Biology 2020 21:26
    Content type: Research article Published on:

  17. Reversible cell cycle arrest (quiescence/G0) is characteristic of adult stem cells and is actively controlled at multiple levels. Quiescent cells also extend a primary cilium, which functions as a signaling hu...

    Authors: Nisha Venugopal, Ananga Ghosh, Hardik Gala, Ajoy Aloysius, Neha Vyas and Jyotsna Dhawan
    Citation: BMC Molecular and Cell Biology 2020 21:25
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Molecular and Cell Biology 2024 25:17

  18. Progesterone Receptor Membrane Component 1 (PGRMC1) is expressed in many cancer cells, where it is associated with detrimental patient outcomes. It contains phosphorylated tyrosines which evolutionarily preced...

    Authors: Bashar M. Thejer, Partho P. Adhikary, Amandeep Kaur, Sarah L. Teakel, Ashleigh Van Oosterum, Ishith Seth, Marina Pajic, Katherine M. Hannan, Megan Pavy, Perlita Poh, Jalal A. Jazayeri, Thiri Zaw, Dana Pascovici, Marina Ludescher, Michael Pawlak, Juan C. Cassano…
    Citation: BMC Molecular and Cell Biology 2020 21:24
    Content type: Research article Published on:

  19. Intervertebral disc degeneration (IDD) is characterized by the loss of nucleus pulposus cells (NPCs) and phenotypic abnormalities. Accumulating evidence suggests that long noncoding RNAs (lncRNAs) are involved...

    Authors: Hongyu Zheng, Tingting Wang, Xiangmin Li, Wei He, Zhiqiang Gong, Zhenkai Lou, Bing Wang and Xingguo Li
    Citation: BMC Molecular and Cell Biology 2020 21:23
    Content type: Research article Published on:

  20. Collagen is a structural protein that provides mechanical stability and defined architectures to skin. In collagen-based skin disorders this stability is lost, either due to mutations in collagens or in the ch...

    Authors: Essak S. Khan, Shrikrishnan Sankaran, Lorena Llontop and Aránzazu del Campo
    Citation: BMC Molecular and Cell Biology 2020 21:22
    Content type: Research article Published on:

  21. Ubiquitination and ubiquitin-like protein post-translational modifications play an enormous number of roles in cellular processes. These modifications are constituted of multistep reaction cascades. Readily im...

    Authors: Gabriel Fenteany, Paras Gaur, Gaurav Sharma, Lajos Pintér, Ernő Kiss and Lajos Haracska
    Citation: BMC Molecular and Cell Biology 2020 21:21
    Content type: Methodology article Published on:

  22. Acute myocardial infarction (AMI) is the leading cause of death globally and has thus placed a heavy burden on healthcare. Tanshinone IIA (TSA) is a major active compound, extracted from Salvia miltiorrhiza Bu...

    Authors: Liye Chen, Lili Wei, Qiongyang Yu, Haozhe Shi and George Liu
    Citation: BMC Molecular and Cell Biology 2020 21:20
    Content type: Research article Published on:

  23. Transcriptional responses required to maintain cellular homeostasis or to adapt to environmental stress, is in part mediated by several nucleic-acid associated proteins. In this study, we sought to establish a...

    Authors: Nastassja L. Kriel, Tiaan Heunis, Samantha L. Sampson, Nico C. Gey van Pittius, Monique J. Williams and Robin M. Warren
    Citation: BMC Molecular and Cell Biology 2020 21:19
    Content type: Research article Published on:

  24. Congenital dyserythropoietic anemia type I (CDA I), is an autosomal recessive disease with macrocytic anemia in which erythroid precursors in the bone marrow exhibit pathognomonic abnormalities including spong...

    Authors: Grace Swickley, Yehoshua Bloch, Lidor Malka, Adi Meiri, Sharon Noy-Lotan, Amiel Yanai, Hannah Tamary and Benny Motro
    Citation: BMC Molecular and Cell Biology 2020 21:18
    Content type: Research article Published on:

  25. dADD1 and dXNP proteins are the orthologs in Drosophila melanogaster of the ADD and SNF2 domains, respectively, of the ATRX vertebrate’s chromatin remodeler, they suppress position effect variegation phenotypes a...

    Authors: Silvia Meyer-Nava, Amada Torres, Mario Zurita and Viviana Valadez-Graham
    Citation: BMC Molecular and Cell Biology 2020 21:17
    Content type: Research article Published on:

  26. Following publication of the original article [1], an error was reported in the tagging of Eugene H. Johnson and Remya R. Nair in the author group.

    Authors: Yasmin ElTahir, Amna Al-Araimi, Remya R. Nair, Kaija J. Autio, Hongmin Tu, Jack C. Leo, Waleed Al-Marzooqi and Eugene H. Johnson
    Citation: BMC Molecular and Cell Biology 2020 21:16
    Content type: Correction Published on:

    The original article was published in BMC Molecular and Cell Biology 2019 20:55

  27. Tartrate–resistant acid phosphatase (TRAP/ ACP5) belongs to the binuclear metallophosphatase family and is present in two isoforms. The primary translation product is an uncleaved TRAP 5a isoform with low phos...

    Authors: Anja Reithmeier, Maria Norgård, Barbro Ek-Rylander, Tuomas Näreoja and Göran Andersson
    Citation: BMC Molecular and Cell Biology 2020 21:15
    Content type: Research article Published on:

  28. Fibronectin (FN) assembly into an insoluble fibrillar matrix is a crucial step in many cell responses to extracellular matrix (ECM) properties, especially with regards to the integrin-related mechanosensitive ...

    Authors: David Gagné, Yannick D. Benoit, Jean-François Groulx, Pierre H. Vachon and Jean-François Beaulieu
    Citation: BMC Molecular and Cell Biology 2020 21:14
    Content type: Research article Published on:

  29. Alzheimer’s disease is the most common neurodegenerative disease in the elderly. Amyloid-β protein (Aβ) is the major component of neuritic plaques which are the hallmark of AD pathology. β-site APP cleaving en...

    Authors: Kaixin Qiu, Wenping Liang, Shuai Wang, Tingting Kong, Xin Wang, Chunyan Li, Zhe Wang and Yili Wu
    Citation: BMC Molecular and Cell Biology 2020 21:13
    Content type: Research article Published on:

  30. Gap junction protein alpha 3 (GJA3), an important pathogenic gene of congenital cataracts, encodes the transmembrane protein connexin46, which functions as an intercellular channel for voltage and chemical gating...

    Authors: Mingzhou Zhang, Chen Huang, Zhenyu Wang, Huibin Lv and Xuemin Li
    Citation: BMC Molecular and Cell Biology 2020 21:12
    Content type: Research article Published on:

  31. Following publication of the original article [1], the authors reported an error that occurred during the production process.

    Authors: Xiaoyan Guo, Dianke Chen, Qingxian Cai, Zhanlian Huang, Wenxiong Xu, Liang Peng and Ping Chen
    Citation: BMC Molecular and Cell Biology 2020 21:10
    Content type: Correction Published on:

    The original article was published in BMC Molecular and Cell Biology 2020 21:6

  32. Gene transfer by electroporation is an established method for the non-viral mediated transfection of mammalian cells. Primary cells pose a particular challenge for electroporation-mediated gene transfer, since...

    Authors: Iqbal Hyder, Shahin Eghbalsaied and Wilfried A. Kues
    Citation: BMC Molecular and Cell Biology 2020 21:9
    Content type: Methodology article Published on:

  33. TgDCX is a doublecortin-domain protein associated with the conoid fibers, a set of strongly curved non-tubular tubulin-polymers in Toxoplasma. TgDCX deletion impairs conoid structure and parasite invasion. TgDCX ...

    Authors: Jacqueline M. Leung, Eiji Nagayasu, Yu-Chen Hwang, Jun Liu, Phillip G. Pierce, Isabelle Q. Phan, Robin A. Prentice, John M. Murray and Ke Hu
    Citation: BMC Molecular and Cell Biology 2020 21:8
    Content type: Research article Published on:

  34. Interferon-alpha (IFNα) is a first-line treatment option for chronic hepatitis B virus (HBV) infection, but the severe systemic side-effects limited its clinical application. Interferon-lambda (IFNλ) with comp...

    Authors: Xiaoyan Guo, Dianke Chen, Qingxian Cai, Zhanlian Huang, Wenxiong Xu, Liang Peng and Ping Chen
    Citation: BMC Molecular and Cell Biology 2020 21:6
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Molecular and Cell Biology 2020 21:10

  35. The tumor suppressor p53 is a major regulator of the DNA damage response and has been suggested to selectively bind and activate cell-type specific gene expression programs. However recent studies and meta-ana...

    Authors: Antonina Hafner, Lyubov Kublo, Michael Tsabar, Galit Lahav and Jacob Stewart-Ornstein
    Citation: BMC Molecular and Cell Biology 2020 21:5
    Content type: Research article Published on:

  36. PM2.5 is associated closely with an increased risk of membranous nephropathy (MN), however, whether PM2.5 could induce podocytes injury, the underlying pathology for MN, has not be thoroughly studied. Triptoli...

    Authors: Qiang Wan, Zhongyong Liu, Ming Yang, Peng Deng, Nana Tang and Yanwei Liu
    Citation: BMC Molecular and Cell Biology 2020 21:4
    Content type: Research article Published on:

  37. ZNF143 is an important transcriptional regulator protein conserved in metazoans and estimated to bind over 2000 promoter regions of both messenger RNA and small nuclear RNA genes. The use of zebrafish is a use...

    Authors: Laura Huning and Gary R. Kunkel
    Citation: BMC Molecular and Cell Biology 2020 21:3
    Content type: Research article Published on:

  38. Monoclonal antibodies (mAbs) and their derivatives have become one of the most important classes of therapeutic drugs. Their multiple applications increased the interest for understanding their complex structu...

    Authors: Mercè Farràs, Ramón Román, Marc Camps, Joan Miret, Óscar Martínez, Xavier Pujol, Antoni Casablancas and Jordi Joan Cairó
    Citation: BMC Molecular and Cell Biology 2020 21:2
    Content type: Research article Published on:

  39. In the bovine placenta, intimate fetomaternal contacts are restricted to discrete placentomes. Here, widely branched fetal chorionic villi interdigitate with corresponding maternal caruncular crypts. The fetal...

    Authors: Marina Polei, Juliane Günther, Dirk Koczan and Rainer Fürbass
    Citation: BMC Molecular and Cell Biology 2020 21:1
    Content type: Research article Published on:

  40. PAX8 was not only a mitotic factor, but identified as a transcription factor involved in the prognosis of human tumor patients. Elucidating the function of PAX8 on the pathology of stomach cancer was meaningful.

    Authors: Liang-Yu Bie, Ning Li, Wen-Ying Deng, Xiao-Yu Lu, Ping Guo and Su-Xia Luo
    Citation: BMC Molecular and Cell Biology 2019 20:61
    Content type: Research article Published on:

    The Retraction Note to this article has been published in BMC Molecular and Cell Biology 2021 22:31

  41. The biological process known as post-translational modification (PTM) is a condition whereby proteomes are modified that affects normal cell biology, and hence the pathogenesis. A number of PTMs have been disc...

    Authors: Abel Chandra, Alok Sharma, Abdollah Dehzangi, Daichi Shigemizu and Tatsuhiko Tsunoda
    Citation: BMC Molecular and Cell Biology 2019 20(Suppl 2):57
    Content type: Research Published on:

    This article is part of a Supplement: Volume 20 Supplement 2

  42. Toll-like receptor 9 is a key innate immune receptor involved in detecting infectious diseases and cancer. TLR9 activates the innate immune system following the recognition of single-stranded DNA oligonucleoti...

    Authors: Varun Khanna, Lei Li, Johnson Fung, Shoba Ranganathan and Nikolai Petrovsky
    Citation: BMC Molecular and Cell Biology 2019 20(Suppl 2):56
    Content type: Research Published on:

    This article is part of a Supplement: Volume 20 Supplement 2

  43. ZNF746 and ZNF777 belong to a subset of the large Krüppel-associated box (KRAB) zinc finger (ZNF) transcription factor family. They contain, like four other members in human, an additional conserved domain, th...

    Authors: Mohannad Al Chiblak, Felix Steinbeck, Hans-Jürgen Thiesen and Peter Lorenz
    Citation: BMC Molecular and Cell Biology 2019 20:60
    Content type: Research article Published on:

  44. Multicellular entities like mammalian tissues or microbial biofilms typically exhibit complex spatial arrangements that are adapted to their specific functions or environments. These structures result from int...

    Authors: Jukka Intosalmi, Adrian C. Scott, Michelle Hays, Nicholas Flann, Olli Yli-Harja, Harri Lähdesmäki, Aimée M. Dudley and Alexander Skupin
    Citation: BMC Molecular and Cell Biology 2019 20:59
    Content type: Research Article Published on:

  45. In many important life activities, the execution of protein function depends on the interaction between proteins and ligands. As an important protein binding ligand, the identification of the binding site of t...

    Authors: Shan Wang, Xiuzhen Hu, Zhenxing Feng, Xiaojin Zhang, Liu Liu, Kai Sun and Shuang Xu
    Citation: BMC Molecular and Cell Biology 2019 20(Suppl 3):53
    Content type: Research Published on:

    This article is part of a Supplement: Volume 20 Supplement 3

  46. Proteins perform their functions by interacting with acid radical ions. Recently, it was a challenging work to precisely predict the binding residues of acid radical ion ligands in the research field of molecu...

    Authors: Liu Liu, Xiuzhen Hu, Zhenxing Feng, Xiaojin Zhang, Shan Wang, Shuang Xu and Kai Sun
    Citation: BMC Molecular and Cell Biology 2019 20(Suppl 3):52
    Content type: Research Published on:

    This article is part of a Supplement: Volume 20 Supplement 3

  47. Astral microtubules emanating from the mitotic centrosomes play pivotal roles in defining cell division axis and tissue morphogenesis. Previous studies have demonstrated that human transforming acidic coiled-c...

    Authors: Resmi Rajeev, Puja Singh, Ananya Asmita, Ushma Anand and Tapas K. Manna
    Citation: BMC Molecular and Cell Biology 2019 20:58
    Content type: Research article Published on:

  48. Brucella is a facultative intracellular pathogen responsible for zoonotic disease brucellosis. Little is known about the molecular basis of Brucella adherence to host cells. In the present study, the possible rol...

    Authors: Yasmin ElTahir, Amna Al-Araimi, Remya R. Nair, Kaija J. Autio, Hongmin Tu, Jack C. Leo, Waleed Al-Marzooqi and Eugene H. Johnson
    Citation: BMC Molecular and Cell Biology 2019 20:55
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Molecular and Cell Biology 2020 21:16

  49. Reactive oxygen species (ROS) produce different lesions in DNA by ROS-induced DNA damage. Detection and quantification of 8-oxo-7,8-dihydroguanine (8-oxoG) within cells are important for study. Human ribosomal...

    Authors: Dong Min Kang, Jong-Il Shin, Ji Beom Kim, Kyungho Lee, Ji Hyung Chung, Hye-Won Yang, Kil-Nam Kim and Ye Sun Han
    Citation: BMC Molecular and Cell Biology 2019 20:54
    Content type: Research article Published on:

  50. Mesenchymal stromal cells in the endosteal niche lining compact bone (CB-MSCs) represent a heterogeneous population, all of which contribute to bone repair and remodelling. Hyperglycaemia associated with type ...

    Authors: Ahmed Makki A. Al-Qarakhli, Norhayati Yusop, Rachel J. Waddington and Ryan Moseley
    Citation: BMC Molecular and Cell Biology 2019 20:51
    Content type: Research article Published on:
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