Table 1 Morphological changes in A2058 cells on increasing moduli substrates for control and FMNL2 depleted cells
From: The formin FMNL2 plays a role in the response of melanoma cells to substrate stiffness
| Â | Control | k/d D1 | ||||||
|---|---|---|---|---|---|---|---|---|
Modulus (kPa) | A (µm2) | P (µm) | FD (µm) | R | A (µm2) | P (µm) | FD (µm) | R |
0.2 | 951 ± 8 | 144.9 ± 0.8 | 44.1 ± 0.2 | 0.763 ± 0.002 | 897 ± 7 | 149.5 ± 0.8 | 46.7 ± 0.1 | 0.714 ± 0.002 |
0.5 | 947 ± 9 | 143.7 ± 0.7 | 44.2 ± 0.2 | 0.742 ± 0.002 | 910 ± 6 | 150.4 ± 0.9 | 47.5 ± 0.1 | 0.683 ± 0.002 |
2.0 | 1030 ± 8 | 154.7 ± 0.7 | 47.5 ± 0.1 | 0.704 ± 0.001 | 923 ± 7 | 158.3 ± 0.8 | 50.6 ± 0.2 | 0.633 ± 0.001 |
8.0 | 1050 ± 8 | 165 ± 0.8 | 52.9 ± 0.1 | 0.663 ± 0.001 | 961 ± 6 | 171.3 ± 0.9 | 55.8 ± 0.2 | 0.583 ± 0.001 |