Table 1 Proteins with decreased (bold) or increased (italic) phosphorylation by 1.5-fold or more in DLK-depleted cells
Protein name | Gene symbol | Log2-fold-change | P value | Phosphopeptide sequence |
|---|---|---|---|---|
Nestin | Nes | -1,32 | 2,20E-05 | APLVGSPVHLGPSQPLK |
Transcription factor Jun | Jun | -1,14 | 3,22E-03 | LASPELER |
Histone H1.1 | Hist1h1a | -1,03 | 2,06E-02 | GTGAAGSFK |
Transcription factor Jun | Jun | -1,02 | 4,94E-03 | NSDLLTSPDVGLLK |
Anion exchange protein | Slc4a7 | -1,00 | 3,14E-02 | GNGSGGSRENSTVDFSK |
Histone H1.4 | Hist1h1e | -0,95 | 9,89E-03 | GTGASGSFK |
ATP-citrate synthase | Acly | -0,89 | 5,45E-03 | TASFSESR |
Nestin | Nes | -0,87 | 1,50E-05 | VSQVSLESLEKENVQSPR |
Protein prune homolog 2 | Prune2 | -0,85 | 3,10E-02 | DSGPESPGRTPEPFLSLSLDK |
Eukaryotic translation initiation factor 4B | Eif4b | -0,83 | 4,14E-02 | SSNPPARSQSSDTEQPSPTSGGGK |
Anion exchange protein | Slc4a7 | -0,81 | 9,94E-03 | GSLLQIPVK |
MARCKS-related protein | Marcksl1 | -0,77 | 5,44E-04 | AAATPESQEPQAK |
Transcriptional regulator ATRX | Atrx | -0,66 | 1,07E-02 | QTESNPAMSNSDEESNGTMK |
Neural cell adhesion molecule 1 | Ncam1 | -0,65 | 2,80E-03 | DESKEPIVEVR |
Pogo transposable element with ZNF domain | Pogz | -0,64 | 2,38E-03 | SLDAEPSVPSAAKPSSPEK |
RNA-binding protein 28 | Rbm28 | -0,63 | 4,79E-02 | VEEQVEDSDDEEDDDSHDDEEER |
Band 4.1-like protein 3 isoform 8 | Epb41l3 | -0,63 | 3,16E-02 | TDTAADGETSATESDQEEDAEIK |
Serine/arginine repetitive matrix protein 2 | Srrm2 | -0,62 | 6,79E-03 | RSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPAQPEVALK |
Bromodomain-containing protein 7 | Brd7 | -0,60 | 4,97E-02 | SLQDLDMSSPEDEGQTR |
Anion exchange protein | Slc4a7 | -0,60 | 1,70E-02 | SFADIGK |
Rho guanine nucleotide exchange factor 2 | Arhgef2 | -0,60 | 2,67E-03 | EAQELGSPEDR |
Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 | Nucks1 | -0,59 | 1,34E-02 | NSQEDSEDSEEKDVK |
A-kinase anchor protein 12 | Akap12 | -0,59 | 5,48E-03 | AEADASGNLTKESPDTNGPK |
Myristoylated alanine-rich C-kinase substrate | Marcks | 0,59 | 7,57E-03 | GEATAERPGEAAVASSPSKANGQENGHVK |
Myb-binding protein 1 A | Mybbp1a | 0,59 | 1,60E-02 | DIPSDTQSPVSTKR |
Interferon gamma receptor 1 | Ifngr1 | 0,59 | 1,09E-02 | ALEAGGSTSAMTPDSPPTPTQR |
T-box transcription factor TBX2 | Tbx2 | 0,61 | 1,92E-02 | SAAPLGRSPSRDASPAR |
Protein SET | Set | 0,63 | 3,90E-02 | SASPGLPK |
Ubiquitin carboxyl-terminal hydrolase 34 | Usp34 | 0,64 | 6,20E-03 | EVLTPTSTSDNETR |
MARCKS-related protein | Marcksl1 | 0,71 | 3,03E-02 | EGGGDSSASSPTEEEQEQGEMSACSDEGTAQEGK |
La-related protein 1 | Larp1 | 0,73 | 1,07E-02 | AVTPVPTKTEEVSNLK |
5’-3’ exoribonuclease 2 | Xrn2 | 0,88 | 3,68E-02 | RNSLGGDVLFVGK |