Skip to main content
Fig. 6 | BMC Molecular and Cell Biology

Fig. 6

From: Quantitative phosphoproteomics reveals that nestin is a downstream target of dual leucine zipper kinase during retinoic acid-induced neuronal differentiation of Neuro-2a cells

Fig. 6

Hypothetical model of DLK-mediated nestin regulation in RA-treated Neuro-2a cells. RA activates the DLK-JNK signaling pathway, which subsequently enhances nestin gene expression through the action of specific transcription factors (TFs) and/or chromatin regulatory proteins (CRPs). Alternatively, or in addition (as indicated by dotted arrows), DLK may contribute to nestin protein accumulation in RA-treated cells by promoting its synthesis and/or its stability

Back to article page

BMC Molecular and Cell Biology

ISSN: 2661-8850

Contact us