Fig. 4

(A) The MD simulation of vaccine constructs. (B) The Ramachandran plot analysis through MolProbity of the refined model with the crude model demonstrated 90.1% of the residues in the favored region. (C) The RMSF (fluctuations in residues) showed mean residue fluctuation value of 3.1 Ã… (maximum of 3.9 Ã…) (E) a RMSD graph showing minute change going towards stability at the end (F) The beta factor plot showed that the vaccinal construct has flexible binding characteristics. (D) Molecular dynamic simulation of multiple variables