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Fig. 5 | BMC Molecular and Cell Biology

Fig. 5

From: LEP O-GlcNAcylation inactivates NF-κB pathway by suppressing LEP protein level and thus mediates cellular senescence and osteogenic differentiation in mouse mesenchymal stem cells

Fig. 5

LEP promoted osteoporosis through the activation of NF-κB signaling pathway (A) The DEGs in C3H10T1/2 cells with or without LEP knockdown were shown in a heatmap. (B) Bubble diagram of KEGG pathway enrichment analysis. (C) The protein levels of p65 were assessed by western blot. (D) Western blot was performed to measure the protein levels of p65 in cytoplasm and nucleus

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