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Fig. 2 | BMC Molecular and Cell Biology

Fig. 2

From: LEP O-GlcNAcylation inactivates NF-κB pathway by suppressing LEP protein level and thus mediates cellular senescence and osteogenic differentiation in mouse mesenchymal stem cells

Fig. 2

Etoposide increased LEP expression and promotes cellular senescence in C3H10T1/2 cells (A) The expression of LEP was measured using qPCR. (B and C) Cellular senescence was assessed by β-galactosidase staining. (D and E) qPCR was performed to measure the expression of aging markers p21 and p16. (F) The protein levels of p21 and p16 were evaluated by western blot

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BMC Molecular and Cell Biology

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