Fig. 3

DUOX1 knockdown reversed DOX-induced ROS production and pyroptosis. A DUOX1 knockdown reversed DOX-induced ROS production, tested by flow cytometry. B DUOX1 knockdown reversed DOX-induced pyroptosis, tested by flow cytometry. **p < 0.01 vs. control; ^^p < 0.01 vs. shNC + DOX (2 µmol/L)