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Fig. 4 | BMC Molecular and Cell Biology

Fig. 4

From: TNFα induces Caspase-3 activity in hematopoietic progenitor cells CD34+, CD33+, and CD41 + of myelodysplastic syndromes

Fig. 4

Scheme of Apoptosis Mechanism on MDS Hematopoesis Progenitor Cell by.  TNFα. Early hematopoesis progenitor cell express CD34 + surface marker. Then it will differentiate into specific myeloid progenitor (CD33+), megakaryocyte-thrombocyte progenitor (CD41+). This image illustrates that TNFα induces apoptosis in MDS hematopoesis progenitor cell, especially to cell that have differentiated into myeloid CD33 + and megakaryocyte-thrombocyte CD41+

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