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Fig. 5 | BMC Molecular and Cell Biology

Fig. 5

From: N-Acetyl-L-cysteine facilitates tendon repair and promotes the tenogenic differentiation of tendon stem/progenitor cells by enhancing the integrin α5/β1/PI3K/AKT signaling

Fig. 5

NAC treatment protects from tendon injury and promotes tenogenic differentiation of TSPCs in rats. Male Sprague-Dawley rats were randomized and subjected to the sham procedure (N group) or tendon injury, and the injured rats were randomized and treated with PBS (PBS group) or NAC (NAC group) for 4 or 8 weeks. Their tendon tissues were dissected and their tendon tissue sections were stained with hematoxylin and eosin or immunohistochemistry. Data are representative images or expressed as the mean ± SD of each group (n = 3 per time and group). A The contents of GSH and MDA in different groups of animals. B Histological analyses of tendon tissue morphology. C Immunohistochemistry analyses of the expression of indicated proteins in the tendon tissues of rats. *P < 0.05, **P < 0.01

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BMC Molecular and Cell Biology

ISSN: 2661-8850

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