Fig. 2

Inhibition of the SHH signaling pathway reduces the ability of proliferation, migration and invasion of ESCs. A Effects of different concentrations of GANT61 (10 μmol/L, 20 μmol/L and 30 μmol/L) on the proliferation of ESCs. B Effects of different concentrations of GANT61 on the migration of ESCs. Scale = 1000 μm. C Effect of GANT61 (30 mol/L) on the invasive ability of ESCs. D Quantitative plots of the number of invasive cells in the control group and the GANT61 group