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Fig. 6 | BMC Molecular and Cell Biology

Fig. 6

From: The 3D nuclear conformation of the major histocompatibility complex changes upon cell activation both in porcine and human macrophages

Fig. 6

Single nucleus analysis of MHC allele conformations by 3D-FISH; each allele is defined by three fluorescent spots from BAC containing class I labeled in green with Alexa 488; BAC containing class II in red with Alexa 568; and BAC containing class III in yellow with Alexa 633. a 3D images displaying examples of the three types of nucleus patterns were shown from the captured images obtained with VOLOCITY software. b-c Analysis of LPS/IFNγ activation effects on the allele conformations. Bar graphs represent the percentage of cells in each pattern

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BMC Molecular and Cell Biology

ISSN: 2661-8850

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