Fig. 1

Virus miRNAs and distribution of putative quadruplex forming sequences (PQS). (a) Distribution of virus-encoded miRNAs across virus families; herpesviruses account for more than 90% of all virus-encoded miRNAs. (b) About 67% of all putative herpesvirus miRNA promoters were found to possess at least 1 putative quadruplex forming sequence (PQS) motif as analyzed by Quadparser [61]