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Fig. 7 | BMC Molecular and Cell Biology

Fig. 7

From: Alix and Syntenin-1 direct amyloid precursor protein trafficking into extracellular vesicles

Fig. 7

APP endoplasmic reticulum  (ER) and Golgi localization is altered in the absence of Alix and Syntenin-1. Cells expressing GFP-tagged APPswe were stained with an (a) Blue-white fluorescent ER marker, (b) RFP-tagged Golgi network marker, or (c) monodansylcadaverine (MDC) before live-cell imaging on a Zeiss LSM 880 confocal microscope. Images are representative across at least three independent experiments. Scale bar = 20 μm. Pearson’s Correlation Coefficient (PCC) calculated from ≥10 cells. One-way ANOVA: **, p < 0.01; *, p < 0.05

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BMC Molecular and Cell Biology

ISSN: 2661-8850

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