Fig. 2

Expression levels of HOTAIR, as well as OA- and cartilage-related genes in SW1353 cells at 48 h after (a) siRNA-mediated knockdown of HOTAIR or (b) over-expression of HOTAIR by retrovirus infection. Relative mRNA expression is determined by real-time qRT-PCR and normalised to GAPDH. The HOTAIR knockdown and over-expression groups are expressed as a fold difference from their respective controls. *P < 0.05