Figure 3

Effect of PBP10 on cytosolic calcium mobilization induced by peptide agonists. Neutrophil intracellular calcium mobilization was analyzed by monitoring Fura-2 fluorescence upon stimulation with the FPR agonist fMLF (100 nM; left) or the FPRL1 agonist WKYMVM (100 nM; right) in the absence (upper curves) or presence (lower curves) of PBP10 (1 μM). The curves are derived from a representative experiment. The calcium concentrations given in the right hand part of the figure are valid for the fMLF as well as the WKYMVM induced responses.